Personnel de l'université

Sophie LIMOU

Professor in human genetics and CR2TI Team 3 leader • Centrale Nantes | Mathematics, Informatics and Biology (MIB) department • CR2TI Inserm UMR1064 | iTHINK (Integrative Transplantation, HLA, Immunology and geNomics of Kidney injury) team 3


30 bd Jean Monnet, Nantes • 1 bd de la Noë, Nantes -

Site internet

Discipline(s) enseignée(s)

Cell Biology
Molecular Biology
Human Genomics
Big data

Thèmes de recherche

My research focuses on defining the genetic determinants of complex diseases (genetic epidemiology) using genomics, bioinformatics and biostatistics. After investigating the molecular factors impacting HIV replication and progression to AIDS, I started exploring the renal complications occurring in HIV-infected subjects to progressively dive into the exploration of determinants for kidney function and renal pathologies. My ambition is to develop nephrogenomics in order to decipher the molecular pathways underlying (1) kidney diseases leading to end-stage renal disease (requiring dialysis or kidney transplantation), (2) kidney graft survival, (3) kidney transplantation comorbidities (e.g. infections, cancers), (4) kidney disease recurring after kidney transplantation, (5) kidney function in living kidney donors. By integrating this information with clinical and biological data, we hope to accelerate the translation to clinical care and personalized medicine.

Keywords: human genomics, bioinformatics, epidemiology, biostatistics, populational diversity, health disparity, systemic explorations of complex traits and diseases, development of genomic-related bioinformatics applications, infectious disease, nephrology, kidney transplantation, biomarkers, precision medicine.

Mis à jour le 04 avril 2024.