Patrick GIRAUDEAU

-Full professor
-Junior Fellow of the Institut Universitaire de France
-Vice-president of the Francophone Metabolomics & Fluxomics Society
-Associate Editor, Magnetic Resonance in Chemistry
-Head of Master 2 A3M/ACBPI

Contact details

CEISAM, UMR CNRS 6230 Bât. 22 Faculté des Sciences et Techniques 2 rue de la Houssinière 44322 Nantes Cedex 03

Phone
0251125709 (n° interne : 455709)
Fax
02 51 12 57 12
Email
patrick.giraudeau@univ-nantes.fr

Taught academic discipline(s)

NMR spectroscopy, other spectroscopic methods (MS, IR, UV), computing tools for chemists

Research topics

NMR Methodological developments for quantitative analysis

Activities / Resume

Research area

More information here

  • Methodological developments in fast quantitative 2D NMR
  • Dissolution-DNP
  • Applications to metabolomics, fluxomics, isotopomics
  • Methodological developments in benchtop NMR
  • Applications to reaction monitoring

Funded projects

-ERC Consolidator Grant SUMMIT, (2019-2024)
-PRC France-Israel CNRS-MOST U2NMR (2018-2020)
-ANR SUMMIT (2017-2019)
-Région Pays de Loire RFI Food 4.2 LIPIDOTOOL (2015-2018)
-Région Pays de Loire RésoNantes (2014-2017)
-ANR Starting Grant QUANTUM (2011-2014)
-Several collaborations with industry

Positions

2017 : Full Professor - Université de Nantes (France)
2014-2019 : Junior fellow of the Institut Universitaire de France (IUF)
2009-2017 : Associate professor (Maître de Conférences) - Université de Nantes (France)
2008-2009 : Post-doctoral fellow, Weizmann Institute of Science, Rehovot (Israël), group of L. Frydman. Research area : Ultrafast nD NMR of hyperpolarized solutions. Lavoisier Fellowship from the French Ministry of foreign affairs. Feinberg graduate school fellowship.
2005-2008 : PhD student at CEISAM (Université de Nantes, UMR CNRS 6230). PhD directed by Evelyne Baguet et Serge Akoka Subject: Development of quantitative multidimensional NMR.

Education

2012 : Habilitation
2008 : PhD in analytical chemistry with highest distinction
2005 : Master in analytical chemistry with highest distinction
2004 : "Agrégation" (highest scientific competitive exam in France) in physics and chemistry

Editorial activity and expertise

2011-2017: Elected member of the National University Council (CNU - section 31)
Vice-president of the French Metabolomics and Fluxomics Network
Member of the Euromar Board of Trustees

Committee member of the Ampere Society
Associate Editor, Magnetic Resonance in Chemistry

Member of Editorial Board, Analytical Chemistry
Member of Editorial Board, Current Metabolomics

Additional informations

Publications:

Complete list of scientific production (January 2019)

Publications 2018-2019
Féraud, B., Leenders, J., Martineau, E., Giraudeau, P., Govaerts, B., de Tullio, P.
Two data pre-processing workflows to facilitate the discovery of biomarkers by 2D NMR metabolomics
Metabolomics, in press, doi

Castaing-Cordier, T., Bouillaud, D., Bowyer, P., Gonçalves, O., Giraudeau, P., Farjon, J.
Highly-resolved pure-shift spectra on a compact NMR spectrometer
ChemPhysChem, in press, doi

Bouillaud, D., Farjon, J., Gonçalves, O., Giraudeau, P. 2019
Benchtop NMR for the monitoring of bioprocesses
Magn. Reson. Chem., in press, doi

Le, P.M., Milande, C., Martineau, E., Giraudeau, P., Farjon, J. 2019
Quantification of natural products in herbal supplements: a combined NMR approach applied on goldenseal
J. Pharm. Biomed. Anal., 165, 155-161
 

Sokolenko, S., Jézéquel, T., Hajjar, G., Farjon, J., Akoka, S., Giraudeau, P. 2019
Robust 1D NMR lineshape fitting using real and imaginary data in the frequency domain
J. Magn. Reson., 298, 91-100

Cortés-Borda, D. Wimmer, E., Gouilleux, B., Barré, E., Oger, N., Goulamaly, L., Peault, L. Charrier, B., Truchet, C., Giraudeau, P., Rodriguez-Zubiri, M., Le Grognec, E., Felpin,F.-X. 2018
An Autonomous Self-Optimizing Flow Reactor for the Synthesis of Natural Product Carpanone
J. Org. Chem., 83, 14286-14299

Assemat,G.; Gouilleux,B.; Bouillaud,D.; Farjon, J.; Gilard, V.; Giraudeau, P.; Malet-Martino, M. 2018
Diffusion-ordered spectroscopy on a benchtop spectrometer for drug analysis
J. Pharm. Biomed. Anal., 160, 268-275

Coat, R.; Gouilleux, B.; Thouand, G.; Assaf, A.; Arhaliass, A.; Legrand, J.; Thierry, A.; Martineau, E.; Courant, F.; Giraudeau, P.; Gonçalves, O. 2018
Characterizing the Spoilage of Egg Products using Targeted and Non-targeted Approaches. In Alteration of Ovoproducts, Gonçalves, O.; Legrand, J., Eds. Elsevier: 2018; pp 157-258.

Coat, R.; Gouilleux, B.; Arhaliass, A.; Legrand, J.; Thouand, G.; Martineau, E.; Assaf, A.; Giraudeau, P.; Gonçalves, O. 2018
The Potential of Online Analysis Systems for the Chemotyping of the Egg Matrix. In Alteration of Ovoproducts, Gonçalves, O.; Legrand, J., Eds. Elsevier: 2018; pp 259-283.

Goulitquer, S.; Croyal, M.; Lalande, J.; Royer, A.-L.; Guitton, Y.; Arzur, D.; Durand, S.; Le Jossic-Corcos, C.; Bouchereau, A; Potin, P.;  Akoka, S.; Antignac, .J.-P; Krempf, M.; Ferchaud-Roucher, V.; Giraudeau, P.; and L. Corcos 2018
Consequences of blunting the mevalonate pathway in cancer identified by a pluri-omics approach
Nature Cell Death & Disease, 9, 745

Giraudeau, P.;Felpin, F.-X. 2018
Flow reactors integrated with in-line monitoring using benchtop NMR spectroscopy
React. Chem. Eng., 3, 399-413

Marchand, J; Martineau, E.; Guitton, Y.; Le Bizec, B.; Dervilly-Pinel, G; Giraudeau, P. 2018
A multidimensional 1H NMR lipidomics workflow to address chemical food safety issues
Metabolomics, 14:60

Pupier, M.; Nuzillard, J.-M.; Wist, J.; Schlörer, N. E.; Kuhn, S.; Erdelyi, M.; Steinbeck, C.; Williams, A. J.; Butts, C.; Claridge, T. D. W.; Mikhova, B.; Robien, W.; Dashti, H.; Eghbalnia, H. R.; Farès, C.; Adam, C.; Pavel, K.; Moriaud, F.; Elyashberg, M.; Argyropoulos, D.; Pérez, M.; Giraudeau, P.; Gil, R. R.; Trevorrow, P.; Jeannerat, D. 2018
NMReDATA, a standard to report the NMR assignment and parameters of organic compounds.
Magn. Reson. Chem., 56, 703-715

Plainchont, B., Berruyer, P., Dumez, J.-N., Jannin, S., Giraudeau, P. 2018
Dynamic Nuclear Polarization opens new application perspectives for NMR spectroscopy in analytical chemistry
Anal. Chem., 90, 3639-3650

Jézéquel, T., Silvestre, V., Dinis, K., Giraudeau, P., Akoka, S. 2018
Optimized slice-selective 1H NMR experiments combined with highly accurate quantitative 13C NMR using an internal reference method
J. Magn. Reson. 289, 18-25

Farjon, J., Milande, C., Martineau, E., Akoka, S., Giraudeau, P. 2018
The FAQUIRE approach: FAst, QUantitative, hIghly Resolved and sEnsitivity enhanced 1H, 13C data

Anal. Chem., 90, 1845-1851
 

Gouilleux, B., Marchand, J, Charrier, B., Remaud, G.S., Giraudeau, P. 2018
High-throughput authentication of edible oils with benchtop Ultrafast 2D NMR
Food Chem. 244, 153-158
 

Gouilleux, B., Rouger, L., Giraudeau, P. 2018
Ultrafast 2D NMR: methods and applications
Annu. Rep. NMR Spectrosc, 93, 75-144