applied materials
Green and Tunable Animal Protein-Free Microcarriers for Cell Expansion

E. Somville, A.A Kumar, J. Guicheux, B. Halgand, S. Desmoutiers-Champagne, A. Des Rieux, A. Jonas, K. Glinel

ACS Appl Mater Interfaces. 2020 Oct 29. - Download full text

 Catheter Cardiovasc Interv  . 2020 Sep 23
Standardized fractal bench test evaluation of coronary stents: Performances in bifurcation lesions treated by the re‐proximal optimization technique

PG Piriou, M. Bonin, F.Huchet, V. Letocart, T. Manigold, J. Plessis, F. Derimay, J. Veziers, F. Jordana, P. Guerin

Catheter Cardiovasc Interv . 2020 Sep 23 -

European Spine J
Collateral effects of targeting the nucleus pulposus via a transpedicular or transannular surgical route: a combined X-ray, MRI, and histological long-term descriptive study in sheep

C. Decante, J. Clouet, A. Hamel, L. Le Fournier, O. Gauthier, D. Rouleau, J. Lesoeur, B. Halgand, C. Le Visage, J. Guicheux, M. Fusellier

Eur Spine J . 2020 Sep 18 -

Advanced Healthcare
In Situ Forming, Silanized Hyaluronic Acid Hydrogels with Fine Control Over Mechanical Properties and In Vivo Degradation for Tissue Engineering Applications

K. Flegeau, C. Toquet, G. Rethore, C. d'Arros, L. Messager, B. Halgand, D. Dupont, F. Autrusseau, J. Lesoeur, J. Veziers, P. Bordat, A. Bresin , J. Guicheux, V. Delplace, H. Gautier, P. Weiss

Adv Healthc Mater . 2020 Aug 31 - Download full text



The REGOS team of the Inserm U1229-RMeS laboratory is pleased to announce the recent funding of the OVERbone proposal as an ANR collaborative research project. OVERbone will be coordinated by Valérie Geoffroy and Angélique Galvani (Inserm U1229, RMeS) and will be carried out with Pierre Weiss (Inserm U1229, RMeS) and in collaboration with Patricia Abellan and Jean Le Bideau (IMN, CNRS U6502). OVERbone aims to investigate a novel mechanism of bone formation based on extracellular vesicles (EVs) secreted by bone cells, that could be used as therapy for bone regeneration. In addition, OVERbone will demonstrate that these EVs are altered during aging either in quantity or in quality and that this alteration contributes to bone aging.

INSERMLaunching of the second transversal Inserm program dedicated to Aging (AGEMED 2.0)

The STEP Team is happy to announce that the second transversal Inserm program dedicated to Aging (AGEMED 2.0) will receive a 1.5 M€ grant for the next three years. This research program, coordinated by Eric Gilson (Nice), gathers 11 Research teams from Paris, 2 from Marseille and Grenoble and 1 from Montpellier and Nantes (RMeS STEP team, J.Guicheux and C. Vinatier). The long-term vision of this Inserm program on aging is to ameliorate age-related disorders, improving overall healthspan and reducing public health costs. AGEMED 2.0 will be organized around two main axis. The first axis aims at deciphering the cell senescence code to improve healthspan in chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis and osteoarthritis. The second axis deals with integrated approaches to prevent and treat neuroaging disorders in various pre-clinical models. RMeS will receive a financial support for three years to test the efficacy of senolytic compounds in several murine models of osteoarthritis.


Julien NicolasDr. Julien Nicolas

Advanced macromolecular engineering: from biodegradable vinyl materials to anticancer polymer prodrugs

Institut Galien Paris-Sud, CNRS UMR 8612
March 10, 2020, 11h00 - Amphi Ricordeau (Dental Faculty)

RMeS in the spotlight

Science et Vie
Régénérer le squelette : un biocomposite répare les pertes osseuses

Interview of P. Weiss

Sciences et Vie -

Le quotidien du médecin
Les cellules souches porteuses d'espoir dans les lésions dégénératives

Interview of J. Guicheux

Le Quotidien du Médecin Mai 2020 -

New members

S GratilleurSébastien Grastilleur

Sébastien is post-doctoral researcher. He will work on ANR INDEED

He will join our unit on November 1st 2020
His supervisor is Catherine Le Visage

BaptisteBaptiste Charbonnier

Baptiste is post-doctoral researcher. He will work on ANR GIJAW

He will join our unit on November 1st 2020
His supervisors are Pierre Corre & Pierre Weiss

Laura BachirLaura Bachir

Laura is a M2 student. She will work on LFC project which aims to develop a new injectable biomaterial

Se will join our unit on October 12th 2020
Her supervisors are Hélène Gautier, Aurélie Billon & Valérie Geoffroy

Florian SegeronFlorian Segeron

Florian is a M2 student. He will work on the formulation of a hyalurronic acid hydrogel

He will join our unit on October 12th 2020
His supervisors are Alexis Gaudin & Hélène Gautier

Yoan MoreauYoan Moreau

Yoan is an INSERM Technician. He works on SC3M Platform

He joined our unit on October 1st 2020

PhD defense & HDR

GiuliaPhD Defense of Giulia Frangi

Giulia will defend her thesis on December 15th, 2020 at 2.00 pm (Amphi D. Escande)

Study of the role of PiT2 at the interface between bone and adipose tissues

Directeur de thèse: S. Beck - Co-directeur : L. Beck

Audrey SmithPhD Defense of Audrey Smith

Audrey will defend her thesis on November 10th, 2020 at 2.00 pm(Amphi Ricordeau)

Cellules stromales mésenchymateuses encapsulées dans des microparticules d'alginate : conception et évaluation de leur potentiel anti-arthrosique après injection intra-articulaire chez le lapin

Directeur de thèse: C. Le Visage - Co-directeur : J. Guicheux

CyrilCongratulations to Cyril d'Arros for his PhD Defense !

Cyril defended his thesis on October 2nd, 2020 (Amphi Ricordeau)

Développement d'un substitut osseux hautement malléable et cohésif, un nouveau concept de matrice pour la régénération osseuse

Directeur de thèse: O. Malard - Co-directeur : G. Daculsi

And among other things...

General Assembly 2018

RMeS General Assemby (Campus Gavy - St Nazaire) -
May 14th, 2018

Photo Fête de Noël
Christmas Party RMeS ! December 18th, 2017

Olympiades RMES

The 2nd Edition of the RMeS "Olympiades" has taken place on Sept. 18th, 2017. 4 teams have met in good spirits. Thanks to all the participants!