Bruno BUJOLI

* Chemist-engineer diploma from the National Institute of Industrial Chemistry of Rouen (France), 1982.

* Doctor-engineer diploma (a PhD thesis for engineers) from the University of Nantes, entitled "Regioselectivity of the chemical and electrochemical reductions of 6H-1,3-thiazines", 1985.

* CNRS Charge de Recherche position (the equivalent of assistant professor) at Laboratoire de Synthèse Organique (University of Nantes), 1986.

* PhD thesis diploma from the University of Nantes, entitled. "Chemical Reactivity of the layered FeOCl : possibilities and limits", 1990.

* Post-doctoral position in the Catalysis Department of Rhône-Poulenc Research Center in Aubervilliers (France). "Condensation of p-cresol in ditolylether by gas phase heterogeneous catalysis", 1991.

* Bronze medal of CNRS, 1995.

* CNRS Director of Research position (the equivalent of full professor) at Laboratoire de Synthèse Organique (University of Nantes), 2000.

 * Director of Laboratoire de Synthèse Organique UMR CNRS 6513 (University of Nantes), January 2004

* Director of the CEISAM Laboratory (Chemistry and Interdisciplinarity: Synthesis, Analysis, Modeling) UMR CNRS 6230 (University of Nantes), January 2008

78 publications in international journals (h factor = 22) - 3 patents - 42 invited seminars and conferences - 18 PhD thesis supervisions

 Chemistry and Interdisciplinarity: Synthesis, Analysis, Modeling (CEISAM - UMR 6230 CNRS / University of Nantes)

Functional Materials Engineering - B. BUJOLI (CNRS), P. JANVIER (University of Nantes), M. PETIT (CNRS)


- Coordination chemistry of phosphonic acids (RPO3H2) with metals, yielding metal phosphonates, or how the organic moiety (R) drives the structure of metal phosphonates.

- Surface chemical modification. Organic-inorganic hybrid materials.

- Phosphonic acids, a key function for the preparation of easily reusable catalytic systems: water-soluble catalytic complexes and supported catalysts.

- Applications of hybrid materials in the field of biotechnologies:
Calcium phosphate-based medical devices, active against bone resorption disorders (osteoporosis)
New methodology for the preparation of biological microarrays based on metal phosphonate chemistry (oligonucleotides, ds-DNAs, proteins)

F. FREDOUEIL, M. EVAIN, D. MASSIOT, M. BUJOLI-DOEUFF, B. BUJOLI, J. Mater. Chem., 2001, 11, 1106-1110.
Enantiomerically pure zinc phosphonates based on mixed phosphonic acid-phosphine oxide chiral building blocks.

C. MAILLET, P. JANVIER, M. PIPELIER, T. PRAVEEN, Y. ANDRES et B. BUJOLI, Chem. Mater., 2001, 13, 2879.
Hybrid materials for catalysis ? Design of new phosphonate-based supported catalysts for the hydrogenation of ketones under hydrogen pressure.

I.O. BENITEZ, B. BUJOLI, L.J. CAMUS, C.M. LEE, F. ODOBEL et D.R. TALHAM, J. Am. Chem. Soc., 2002, 124, 4363.
Manganese porphyrin containing zirconium phosphonate films : Monolayers as models for heterogeneous catalysis.

C. MAILLET, T. PRAVEEN, P. JANVIER, S MINGUET, M. EVAIN, C. SALUZZO, L. TOMMASINO et B. BUJOLI, J. Org. Chem., 2002, 67, 8191.
Synthesis of a new water-soluble C2-symmetric chiral diamine : preliminary investigation of its catalytic properties for asymmetric hydrogenation under biphasic conditions.

G. NONGLATON, I.O. BENITEZ, I. GUISLE, M. PIPELIER, J. LEGER, D. DUBREUIL, C. TELLIER, D.R. TALHAM, et B. BUJOLI, J. Am. Chem. Soc., 2004, 126, 1497.
New approach to oligonucleotide microarrays using zirconium phosphonate-modified surfaces.

S. JOSSE, C. FAUCHEUX, A. SOUEIDAN, G. GRIMANDI, D. MASSIOT, B. ALONSO, P. JANVIER, S. LAÏB, P. PILET, O. GAUTHIER, G. DACULSI, J. GUICHEUX, B. BUJOLI et J.M. BOULER, Biomaterials, 2005, 26, 2073-2080.
Novel biomaterials for bisphosphonate delivery.

B. PETER, D.P. PIOLETTI, S. LAÏB, B. BUJOLI, P. PILET, P. JANVIER, J. GUICHEUX, P.-Y. ZAMBELLI, J.-M. BOULER et O. GAUTHIER, Bone, 2005, 36, 52-60.
Calcium phosphate drug delivery system: influence of local Zoledronate release on bone implant osteointegration.

H. ROUSSIERE, G. MONTAVON, S. LAIB, P. JANVIER, B. ALONSO, F. FAYON, M. PETIT, D. MASSIOT, J.-M. BOULER et B. BUJOLI, J. Mater. Chem., 2005, 15(35-36), 3869-3875.
Hybrid materials applied to biotechnologies : coating of calcium phosphates for the design of implants active against bone resorption disorders

T.L. SCHULL, L. HENLEY, J.R. DESCHAMPS, R.J. BUTCHER, D.P. MAHER, C.A. KLUG, K. SWIDER-LYONS, W.J. DRESSICK, B. BUJOLI, A.E. GREENWOOD, L.K. BYINGTON CONGIARDO, D.A. KNIGHT, Organometallics, 2007, 26, 2272-2276.
Organometallic supramolecular mixed-valence cobalt(I)/cobalt(II) aquo complexes stabilized with the water-soluble phosphine ligand p-TPPTP (p-triphenylphosphine triphosphonic acid).

 H. ROUSSIERE, F. FAYON, B. ALONSO, T. ROUILLON, V. SCHNITZLER, E. VERRON, J. GUICHEUX, M. PETIT, D. MASSIOT, P. JANVIER, J.-M. BOULER,  B. BUJOLI, Chem. Mater, 2008, 20, 182-191.
Reaction of Zoledronate with beta-tricalcium phosphate, for the design of potential drug device combined systems

Towards zirconium phosphonate-based microarrays for probing DNA - protein interactions : the critical effect of the location of the probe binding groups.